Articles

The WEB-based Asthma Control: an intriguing connection or a dangerous hazard?

Globally, an estimated 300 million people have asthma, presenting a considerable and increasing burden of disease for healthcare systems, families, and patients themselves. Despite two decades of guidelines, a...

Authors: Carlo Lombardi, Giovanni Passalacqua and Giorgio Walter Canonica

Sickle cell disease: wheeze or asthma?

Sickle cell disease (SCD) is the most common life-limiting genetic disease among African Americans, affecting more than 100,000 people in the United States. Respiratory disorders in patients with sickle cell d...

Authors: Robyn T. Cohen, Elizabeth S. Klings and Robert C. Strunk

Small airway dysfunction and bronchial asthma control : the state of the art

According to national and international guidelines, achieving and maintaining asthma control is a major goal of disease management. In closely controlled clinical trials, good asthma control can be achieved , ...

Authors: Marcello Cottini, Carlo Lombardi and Claudio Micheletto

Genetic and epigenetic studies of FOXP3 in asthma and allergy

Multiple factors interact to trigger allergic diseases, including individual genetic background and factors related to the environment such as exposure to allergens, air pollution and respiratory infections. T...

Authors: Cintia Rodrigues Marques, Ryan Santos Costa, Gustavo Nunes de Oliveira Costa, Thiago Magalhães da Silva, Tatiane Oliveira Teixeira, Emília Maria Medeiros de Andrade, Alana A. Galvão, Valdirene Leão Carneiro and Camila Alexandrina Figueiredo

The school environment and asthma in childhood

In this article, we discuss the relationship between environmental exposures within the school environment and pediatric asthma morbidity. This article will conclude by reviewing novel school based asthma educ...

Authors: Marissa Hauptman and Wanda Phipatanakul

“Asthma can take over your life but having the right support makes that easier to deal with.” Informing research priorities by exploring the barriers and facilitators to asthma control: a qualitative analysis of survey data

Involving patients and the public in research prioritisation is important. Cochrane Airways works with authors to produce systematic reviews of evidence related to chronic airways disease. Cochrane Airways has...

Authors: Rebecca Normansell and Emma Welsh

Vocal cord dysfunction: a review

Vocal cord dysfunction (VCD) is a term that refers to inappropriate adduction of the vocal cords during inhalation and sometimes exhalation. It is a functional disorder that serves as an important mimicker of ...

Authors: Neha M. Dunn, Rohit K. Katial and Flavia C. L. Hoyte

Allergic rhinitis: the “Ghost Diagnosis” in patients with asthma

Allergic rhinitis (AR) is a common comorbidity of asthma that contributes to asthma severity. Although over 80 % of asthmatics have AR, the condition is frequently underdiagnosed in subjects with asthma. AR it...

Authors: Maureen Egan and Supinda Bunyavanich

Psychological aspects in asthma: do psychological factors affect asthma management?

Despite the regular treatment with inhaled corticosteroids (ICS) or ICS plus long-acting beta2-agonists, permits to control de majority of asthmatics, a significant proportion of patients does not respond to t...

Authors: Ilaria Baiardini, Francesca Sicuro, Francesco Balbi, Giorgio Walter Canonica and Fulvio Braido

Allergen immunotherapy in asthma; what is new?

The use and role of allergen immunotherapy (AIT) in asthma is still a matter of debate, and no definite recommendation about this is made in guidelines, both for the subcutaneous and sublingual routes. This is...

Authors: Giovanni Passalacqua, Anthi Rogkakou, Marcello Mincarini and Giorgio Walter Canonica

Exercise-induced bronchoconstriction: new evidence in pathogenesis, diagnosis and treatment

The acute airway narrowing that occurs as a result of exercise is defined exercise-induced bronchoconstriction (EIB). Most recent guidelines recommend distinguishing EIB with underlying clinical asthma (EIB_A) fro...

Authors: Matteo Bonini and Paolo Palange

Asthma research and practice: a new journey begins

Authors: Juan C. Celedon, Giovanni Passalacqua and Giorgio Walter Canonica

The patient with rhinitis in the pharmacy. A cross-sectional study in real life

In the practical management of allergic rhinitis (AR), pharmacists are usually the first-line contact, also because some medications are available as over the counter. Therefore, pharmacists may represent an i...

Authors: Carlo Lombardi, Eleonora Musicco, Francesco Rastrelli, Germano Bettoncelli, Giovanni Passalacqua and Giorgio Walter Canonica

Vitamin D supplementation decreases Aspergillus fumigatus specific Th2 responses in CF patients with aspergillus sensitization: a phase one open-label study

Patients with cystic fibrosis (CF) complicated by allergic bronchopulmonary aspergillosis (ABPA) are vitamin D deficient and in vitro treatment with 1,25 (OH)₂ vitamin D₃ of CD4+ cells from CF patients with ABPA ...

Authors: Nikki Lynn Hue Nguyen, Joseph M. Pilewski, Juan C. Celedón, Sivanarayana Mandalapu, Megan L. Blanchard, Adrienne DeRicco, Elizabeth Hartigan, John F. Alcorn and Jay K. Kolls

Asthma and obesity: mechanisms and clinical implications

Obesity is the most common asthma co-morbidity; it has been associated with increased risk for asthma exacerbations, worse respiratory symptoms and poor control. The exact mechanisms remain elusive and are pro...

Authors: Cynthia Wilson Baffi, Daniel Efrain Winnica and Fernando Holguin