From: Treatment outcome clustering patterns correspond to discrete asthma phenotypes in children
baseline demographics | gender, age |
subjective clinical data | at baseline (personal and family medical history- atopy status, allergic rhinitis (AR), atopic dermatitis (AD), food allergy and other comorbidities) |
objective clinical data | at baseline and other follow-up appointments- symptom control, frequency and severity of exacerbations in the period since the last visit, lung function, airway inflammation (FENO) measurement and medication useat baseline- skin prick and total and specific IgE test results, hematologic and biochemical blood test results, comorbidity status ENT examination, pH probing with impedance for the reflux episodes monitoring for diagnostics of GERD/LPR, polysomnography for diagnostics of OSAS, height and weight for calculation of BMI percentiles |
genetic data | genotypes for rs37973 (GLCCI1), rs9910408 (TBX21), rs242941 (CRHR1), rs1876828 (CRHR1), rs1042713 (ADRB2) and rs17576 (MMP9) |