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Table 1 The definition of uncontrolled asthma [5]

From: Psychological aspects in asthma: do psychological factors affect asthma management?

Uncontrolled asthma defined as at least one of the following:
1) Poor symptom control: ACQ consistently >1.5, ACT <20 (or “not well controlled” according NAEPP/GINA guidelines);
2) Frequent severe exacerbations: two or more bursts of systemic CS (>3 days each) in the previous year;
3) Serious exacerbations: at least one hospitalisation, ICU stay or mechanical ventilation in the previous year;
4) Airflow limitation: after appropriate bronchodilator withhold FEV1 < 80 % predicted (in the face of reduced FEV1/FVC defined as less than the lower limit of normal);
Controlled asthma that worsens on tapering of these high doses of ICS or systemic CS (or additional biologics)
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  1. GINA Global initiative for asthma, ICS Inhaled corticosteroids, LABA, Long-acting beta2-agonists, CS Corticosteroids, ACQ Asthma control questionnaire, ACT Asthma control test, NAEPP National asthma education and prevention program, ICU Intensive care unit, FEV1 Forced expiratory volume in the first second, FVC Forced vital capacity