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Fig. 1 | Asthma Research and Practice

Fig. 1

From: A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype

Fig. 1

 A schematic overview of the procedure in the OVA-induced asthma mouse model. Mice were sensitized to OVA (i.p.) on days 1, 14, and 21 and challenged with OVA aerosol on days 26, 27, and 28 to induce acute allergic airway inflammation. Acute neutrophilic inflammation were provoked by i.t. instillation of the TLR-3 ligand poly(cytidylic-inosinic) acid on day 28. A control group was sham sensitized to PBS and challenged with OVA aerosol. The mice were sacrificed on day 29

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