Table 3 Response variables assessed at each visit (compared to a previous one- 6, 12 and 18 months after baseline). Response to treatment is defined into more detail in the supplementary file (Table S3). ppb- parts per billion
From: Treatment outcome clustering patterns correspond to discrete asthma phenotypes in children
FEV1 | MEF50 | FENO | Asthma control | |
|---|---|---|---|---|
Good | Increase ≥ 10% predicted | Increase ≥ 15% predicted | Decrease < 20% for FENO values > 35 (50) ppb or increase < 10 ppb for FENO values < 35 (50) ppb | improvement in asthma control |
Moderate | ± 9% predicted | ± 14% predicted | ≤ 20% FENO ≤ 20% for FENO values over 35 (50) ppb or ± 10 ppb for FENO values < 35 (50) ppb | no changes in partial asthma control |
Poor | Decrease ≤ (-10%) predicted | Decrease ≤ (-15%) predicted | Increase > 20% for FENO values > 35 (50) ppb or increase > 10 ppb for FENO values < 35 (50) ppb | deterioration in asthma control |