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Table 1 Demographic and disease related data

From: Patient perceived barriers to exercise and their clinical associations in difficult asthma

 WATCH Cohort as a whole (n)Median [IQR]N (%)EBTQ Cohort Baseline Data (n)Median [IQR]N (%)P value
Demographics
 Female501 65.3%62 69.4%ns
 Age at Study Enrolment (years)50152 [38.5, 63.0] 6253.5 [35.75, 65.25] ns
 Age at asthma diagnosis47919 [4, 40] 6223 [3.0, 40.35] ns
 BMI49529.7 [25.6, 35.3] 6029.25 [25.5, 36.23] ns
 Obese495 48.3%62 48.3%ns
 Current or Ex Smokers500 47.6%62 31.1%ns
Co-Morbidities
 Rhinitis446 67.5%62 58.1%ns
 Eczema495 26.1%62 25.8%ns
 Bronchiectasis493 6.9%62 16.1%ns
 GORD495 14.1%61 50%ns
 Depression486 64.8%62 17.7%ns
 Anxiety454 36.8%62 19.4%ns
 Dysfunctional Breathing451 48.7%61 41%ns
 Intermittent Laryngeal Dysfunction476 14.5%59 10.2%ns
 Sulphite Sensitivity447 7.7%62 4.8%ns
 Salicylate Sensitivity493 25.1%62 21%ns
 Sleep Apnoea  7.2%62 6.5%ns
Healthcare Utilisation
  ≥ 1 Asthma Related ICU Visits ever500 28.2%60 1.7%ns
  ≥ 1 Asthma Hospital Admission (last 12 months)497 29.0%62 11.3%P = 0.0025
  ≥ 3 Rescue Oral Corticosteroids (last 12 months)448 43.6%60 31.7%ns
 Maintenance oral corticosteroids steroids479 29.9%   P < .0001
 Biological treatment in last 12 months495 17.6%  39%P = .0016
Blood Test Results
 Eosinophil Count    0.2 [0.1, 0.4] ns
Lung Function Test Results      ns
 FeNO50 (ppb)32919.7 [10.0, 38.7] 6222 [14, 45.5] P = .03
 Post BD FEV1 (%)34175 [59.3, 92.1] 5773.4 [59.5, 86.6] ns
 Post BD FEV1/FVC (ratio)34068 [58, 78] 5772 [56.5, 78] ns
Skin Prick Tests
 Positive to any Aeroallergen391 68.0%52 75%ns
 Positive to Aspergillus355 15.8%47 17%ns
Questionnaires
 ACQ6 Score4672.5 [1.5, 3.5] 622.4 [1.28, 3.2] ns
 Epworth Score4248 [4, 12.75] 558 [3, 11] ns
 HADS Total Score41810.5 [6, 18] 538 [4.0, 15.5] ns
 HADS A Score4256 [3, 10] 555 [3, 9] ns
 HADS D Score4264 [2, 8] 533 [1, 6] P = .04
 Hull Cough Score37825 [14, 36] 4830 [14.25, 41.75] ns
 Nijmegen Score37321 [12, 31] 4721 [13, 26] ns
 SNOT22 Score32431.5 [20, 50] 4036.5 [23.25, 48.75] ns
 EQ_5D_5L Index value1700.72 [0.53, 0.83] 620.72 [0.54, 1.00] ns
 SGRQ Total Score38151.1 [35.25, 67.34] 4959.6 [37.1, 63.4] ns
 SGRQ Symptoms Score41167.73 [50.72, 81.31] 5368 [53, 81.7] ns
 SGRQ Activity Score38966.1 [43.7, 85.7] 5066.2 [41.8, 73.8] ns
 SGRQ Impacts Score39638.71 [22.76, 55.74] 5236 [25.4, 54.1] ns