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Table 1 Potential clinical application and future directions for main exhaled biomarkers

From: Exhaled biomarkers in childhood asthma: old and new approaches

Exhaled Biomarkers

Potential Clinical Applications and Future Directions

feNO

Identification of early-onset asthma among preschool children with recurrent wheezing

Stratification of asthmatic patients according to eosinophilic inflammation (treatable trait)

Analytes measured in EBC

Patient phenotyping and prediction of therapy response based on specific biomarkers profiles

VOCs in exhaled air

Early asthma diagnosis

Patient stratification and phenotyping

  1. feNO fractional exhaled nitric oxide, ICS inhaled corticosteroids, EBC exhaled breath condensate, VOCs volatile organic compounds