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Table 4 Multivariable linear regression analysis of the association between 25(OH)D concentrations and measures of pulmonary function, asthma biomarkers, and asthma control

From: Associations between serum 25(OH)D concentrations and prevalent asthma among children living in communities with differing levels of urbanization: a cross-sectional study

 

Overall (n = 884)

Asthma (n = 413)

Healthy controls (n = 471)

Unadjusted Beta (95% CI)

Adjusteda Beta (95% CI)

Unadjusted Beta (95% CI)

Adjusted Beta (95% CI)

Unadjusted Beta (95% CI)

Adjusted Beta (95% CI)

Pre-bronchodilator FEV1 z-score

−.129 (−0.750 to 0.493)

.0566 (−0.560 to 0.673)

0.0298 (−0.672 to 0.731)

0.153 (−0.464 to 0.769)

−0.484 (−1.56 to 0.592)

−0.178 (−1.28 to 0.92)

p= 0.69

p= 0.86

p= 0.93

p= 0.63

p= 0.38

p= 0.75

Pre-bronchodilator FVC z-score

−0.476 (−1.09 to 0.14)

−0.256 (−0.868 to 0.356)

−0.244 (−0.940 to 0.452)

−0.155 (−0.782 to 0.472)

−0.741 (−1.77 to 0.284)

−0.455 (−1.52 to 0.607)

p= 0.13

p= 0.41

p= 0.49

p= 0.63

p= 0.16

p= 0.40

eNO (ppb)

−.0306 (−.0610 to −0.000369)

−0.0295 (−0.0621 to 0.00308)

−0.0142 (−0.0440 to 0.0156)

−0.0.00798 (−0.0359 to 0.00199)

−0.0518 (−0.115 to 0.0113)

−0.0711 (−0.139 to 0.0305)

p= 0.05

p= 0.08

p= 0.35

p= 0.57

p= 0.11

p= 0.04

Total serum IgE (kUa/L, log scale)

0.269 (−0.278 to 0.816)

0.0494 (−0.676 to 0.775)

0.305 (−0.392 to 1.00)

−0.229 (−1.08 to 0.618)

0.401 (−0.466 to 1.27)

0.202 (−0.926 to 1.33)

p= 0.33

p= 0.89

p= 0.39

p= 0.60

p= 0.36

p= 0.73

ACT score

NA

NA

−0.1477 (−0.420 to 0.126)

−0.116 (−0.322 to 0.893)

NA

NA

p= 0.29

p= 0.27

  1. aAdjusted for season, age, sex, BMI, and SES. Overall model also adjusted for asthma status