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Table 2 FOXP3 epigenetic studies investigated for association with asthma and allergy

From: Genetic and epigenetic studies of FOXP3 in asthma and allergy

Author(s)

Year

n (cases/controls)

Epigenetic marker analyzed

Cell population analysed

Nadeau et al.

2010

32 (16/16)

CpG methylation

Treg cells (CD4+CD25hiCD127lo) and effector T (Teff) cells (CD4+CD25lo/neg)

Brunst et al.

2013

71 (15/56)

CpG methylation

Buccal cells in saliva

Runyon et al.

2012

42 (21/21)

CpG methylation

Treg cells (CD4+ CD25hiCD127lo/neg) and Teff CD4+CD25neg

Kohli et al.

2012

102 (37/65)

CpG methylation

Treg cells (CD4+ CD25hiCD127lo) and Teff CD4+CD25neg

Lluis et al.

2014

43

CpG methylation

Whole blood

Michel et al.

2013

95 (45/50)

CpG methylation

Cord blood and whole blood