Skip to main content

Table 1 FOXP3 SNPs investigated for association with asthma and allergy

From: Genetic and epigenetic studies of FOXP3 in asthma and allergy

SNP

Genomic Position

Alleles

Function

Diseases

N (cases/controls)

Country

Reference

rs3761548

49,261,784

A/C

Intron

Atopy

3062*

The Netherlands

Bottema, 2009

Allergic rhinitis

395

Hungary

Fodor, 2010

(178/217)

Asthma

3062*

The Netherlands

Bottema, 2010

Allergic rhinitis

384

China

Zhang, 2009

(193/191)

Allergic rhinitis

318

Iran

Hassannia, 2011

(153/165)

Allergic rhinitis

708

China

Zhang, 2012

(378/330)

rs2232365

49,259,429

A/G

Intron]

Allergic rhinitis

384

China

Zhang, 2009

(193/191)

Allergic rhinitis

708

China

Zhang, 2012

(378/330)

Allergic rhinitis

318

Iran

Hassannia, 2011

(153/165)

rs6609857

49,245,158

C/T

3’ UTR

Asthma

3062*

The Netherlands

Bottema, 2010

Atopy

3062*

The Netherlands

Bottema, 2009

rs2232368

49,255,822

A/G

Intron

Allergic rhinitis

384

China

Zhang, 2009

(193/191)

rs2232366

49,258,209

G/T

Intron

Allergic rhinitis

384

China

Zhang, 2009

(193/191)

rs2232364

49,259,888

A/C/G/T

Intron

Allergic rhinitis

384

China

Zhang, 2009

(193/191)

rs3761549

49,260,888

C/T

Intron

Atopy

3062*

The Netherlands

Bottema, 2009

rs3761547

49,262,004

A/G

Intron

Allergic rhinitis

384

China

Zhang, 2009

(193/191)

rs2869211

49,264,409

A/T

Intron

Allergic rhinitis

384

China

Zhang, 2009

(193/191)

  1. Cases and controls were not shown for all studies (*) because some studies use different phenotypes and analyze sex and age separately