From: Exercise-induced bronchoconstriction: new evidence in pathogenesis, diagnosis and treatment
Diagnostic procedure | Criteria |
---|---|
Pulmonary function | FEV1 < 70 %, FEV1/VC <55 % |
Bronchodilator test | ↑ FEV1 ≥ 12 % or >200 ml |
Eucapnic Voluntary Hyperpnea (EVH) | ↓ FEV1 ≥ 10 % |
Exercise challenge | ↓ FEV1 ≥ 10 % |
Methacholine challenge | ↓ FEV1 ≥ 20 % with a: |
PC20 ≤ 4 mg/ml (for subjects not taking ICS) | |
or | |
PC20 ≤ 16 mg/ml (for subjects taking ICS for at | |
least 1 month) | |
Hyperosmolar test (Mannitol, Saline) | ↓ FEV1 ≥ 15 % |