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Fig. 2 | Asthma Research and Practice

Fig. 2

From: Vitamin D supplementation decreases Aspergillus fumigatus specific Th2 responses in CF patients with aspergillus sensitization: a phase one open-label study

Fig. 2

Vitamin D supplementation decreases Aspergillus induced IL-13 responses in CD4+ T cells. CD11c + DCs with from patients with confirmed ABPA before (D0) and 8 and 24 weeks after 4000 IU cholecalciferol daily were treated with a) media or b) TSLP (5 ng/ml) and then pulsed with Aspergillus extract. Purified CD4+ T-cells were added for 96 h. Supernatants were harvested and analyzed by Luminex for IL-13 production. Data is graphed as a percentage of the stimulated response (CD3/CD28) for each individual patient at each time point

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